Article
Sleep duration and heart failure risk: Insights from a Mendelian Randomization Study.
Medicine - 13 Sept 2024
Zeng Lianlin, Fu Shasha, Xu Hailan, Zhu Lutao, Li Xiaomei, Cheng Kang, Li Yangan, Hu Kehui
Abstract excerpt
To investigate the causal relationship between sleep duration and heart failure (HF) in a European population. We focused on the continuous sleep duration of 460,099 European individuals as our primary exposure. Genome-wide significant single nucleotide polymorphisms (SNPs, n = 9851,867) linked to continuous sleep duration were adopted as instrumental variables. The outcome of interest was based on HF events in a...
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