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Article

Causal effects of plasma metabolites on chronic kidney diseases and renal function: a bidirectional Mendelian randomization study.

Frontiers in endocrinology - 1 Jan 2024

Zhao Xiaodong, Gao Jialin, Kou Kai, Wang Xi, Gao Xin, Wang Yishu, Zhou Honglan, Li Faping

Abstract excerpt

Background: Despite the potential demonstrated by targeted plasma metabolite modulators in halting the progression of chronic kidney disease (CKD), a lingering uncertainty persists concerning the causal relationship between distinct plasma metabolites and the onset and progression of CKD. Methods: A genome-wide association study was conducted on 1,091 metabolites and 309 metabolite ratios derived from a cohort of...

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Identifiers

PMID: 39129920
DOI: 10.3389/fendo.2024.1429159
PMCID: PMC11310041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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