Article
Impairment of kidney function and kidney cancer: A bidirectional Mendelian randomization study.
Cancer medicine - 1 Feb 2023
Lin Yifei, Yang Yong, Fu Tingting, Lin Ling, Zhang Xingming, Guo Qiong, Chen Zhenglong, Liao Banghua, Huang Jin
Abstract excerpt
BACKGROUND: Many observational epidemiology studies discovered that kidney cancer and impaired kidney function have a bidirectional relationship. However, it remains unclear whether these two kinds of traits are causally linked. In this study, we aimed to investigate the bidirectional causal relation between kidney cancer and kidney function biomarkers (creatinine-based estimated glomerular filtration rate...
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