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Article

Blood metabolites and chronic kidney disease: a Mendelian randomization study.

BMC medical genomics - 28 May 2024

Hou Yawei, Xiao Zhenwei, Zhu Yushuo, Li Yameng, Liu Qinglin, Wang Zhenguo

Abstract excerpt

BACKGROUND: Human blood metabolites have demonstrated close associations with chronic kidney disease (CKD) in observational studies. Nonetheless, the causal relationship between metabolites and CKD is still unclear. This study aimed to assess the associations between metabolites and CKD risk. METHODS: We applied a two-sample Mendelian randomization (MR) analysis to evaluate relationships between 1400 blood...

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Identifiers

PMID: 38807172
DOI: 10.1186/s12920-024-01918-3
PMCID: PMC11131213

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