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Article

Causal association of plasma circulating metabolites with nephritis: a Mendelian randomization study

3 May 2024

Abstract excerpt

Background Nephritis is a pivotal catalyst in chronic kidney disease (CKD) progression. Although epidemiological studies have explored the impact of plasma circulating metabolites and drugs on nephritis, few have harnessed genetic methodologies to establish causal relationships. Methods Through Mendelian randomization (MR) in two substantial cohorts, spanning large sample sizes, we evaluated over 100 plasma...

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PMID: 38765814
DOI: 10.3389/fnut.2024.1364841

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