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Article

Exchanges in the 'a' determinant of the hepatitis B virus surface antigen revisited.

Virology - 1 Nov 2024

Pondé Robério Amorim de Almeida, Amorim Guilherme de Sousa Pondé

Abstract excerpt

The hepatitis B virus surface antigen's (HBsAg) 'a' determinant comprises a sequence of amino acid residues located in the major hydrophilic region of the S protein, whose exchanges are closely associated with compromising the antigenicity and immunogenicity of that antigen. The HBsAg is generally present in the bloodstream of individuals with acute or chronic hepatitis B virus (HBV) infection. It is classically...

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Identifiers

PMID: 39127000
DOI: 10.1016/j.virol.2024.110184

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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