Article
The relationship between interleukin 17A rs2275913 gene polymorphism and circulating IL17A levels and disease activity and severity in Egyptian rheumatoid arthritis patients.
Expert review of clinical immunology - 1 Aug 2025
Abdel Fattah Maha A, Mehanna Eman T, Fattah Shaimaa A, Mesbah Noha M, Saleh Samy M, Abo-Elmatty Dina M, Ibrahim Maha E
Abstract excerpt
OBJECTIVES: IL17A, part of the IL17 cytokine family, is a pivotal player in synovitis present in RA patients. This research focused on assessing how the IL17A rs2275913 genetic variation influences IL17A serum concentration, disease progression, and prognosis in Egyptian RA patients. METHODS: It encompassed a group of 100 healthy individuals and 100 RA patients. The rs2275913 genetic polymorphism was analyzed in...
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