Article
Association between Interleukin-17F 7488A/G and 7383A/G polymorphisms and susceptibility to juvenile idiopathic arthritis.
Pediatric research - 1 Oct 2023
Abd Almonaem Eman Rateb, Shaheen Ashraf Mohamed, Abdelrahman Amira M N, Hassan Waleed A, Daay El Khair Noha Mohamed, Abdel Haie Omima Mohamed
Abstract excerpt
BACKGROUND: Interleukin-17F (IL-17F), one of the cytokines, is crucial in the pathophysiology of juvenile idiopathic arthritis (JIA). Therefore, we aimed to determine the relation between IL17F 7488A/G and IL17F 7383A/G single-nucleotide polymorphisms and JIA susceptibility and to explain their impact on the disease activity. METHODS: Genomic DNA of 70 patients with JIA and 70 age and sex-matched controls were...
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