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ALDH1A1 promotes immune escape of tumor cells through ZBTB7B-glycolysis pathway

7 Aug 2024

Abstract excerpt

The primary impediment to the success of immunotherapy lies in the immune evasion orchestrated by tumors, contributing to the suboptimal overall response rates observed. Despite this recognition, the intricacies of the underlying mechanisms remain incompletely understood. Through preliminary detection of clinical patient tissues, we have found that ALDH1A1 was a key gene for the prognosis of cancer patients and...

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PMID: 39107297
DOI: 10.1038/s41419-024-06943-9

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