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Article

Molecular Characterization and Clinical Relevance of ALDH2 in Human Cancers

13 Jan 2022

Abstract excerpt

Background: Aldehyde dehydrogenase 2 (ALDH2) is well-known to be a key enzyme in alcohol metabolism. However, a comprehensive understanding of ALDH2 across human cancers is lacking. Methods: A systematic and comprehensive analysis of the molecular alterations and clinical relevance for ALDH2 in more than 10,000 samples from 33 cancer types was performed. qRT-PCR was performed on 60 cancer and 60 paired nontumor...

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PMID: 35096916
DOI: 10.3389/fmed.2021.832605

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