Article
When less is more: The association between the expression of polymorphic CYPs and AFB1-induced HCC.
European journal of clinical investigation - 1 Dec 2024
Mohamed Asmaa Ashraf, Armanious Monica, Bedair Rana W, Amin Nada Sherif, El Tayebi Hend M
Abstract excerpt
BACKGROUND: An individual's genetic fingerprint is emerging as a pivotal predictor of numerous disease- and treatment-related factors. Single nucleotide polymorphisms (SNPs) in drug-metabolizing enzymes play key roles in an individual's exposure to a malignancy-associated risk, such as Aflatoxin B1 (AFB1)-induced hepatocellular carcinoma (HCC). AIM: This study aimed at reviewing literature on the polymorphisms...
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