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Article

SWI/SNF Complex-Deficient Undifferentiated Carcinoma of the Pancreas: Clinicopathologic and Genomic Analysis.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Nov 2024

Yavas Aslihan, Ozcan Kerem, Adsay N Volkan, Balci Serdar, Tarcan Zeynep C, Hechtman Jaclyn F, Luchini Claudio, Scarpa Aldo, Lawlor Rita T, Mafficini Andrea, Reid Michelle D, Xue Yue, Yang Zhaohai, Haye Kester, Bellizzi Andrew M, Vanoli Alessandro, Benhamida Jamal, Balachandran Vinod, Jarnagin William, Park Wungki, O'Reilly Eileen M, Klimstra David S, Basturk Olca

Abstract excerpt

Inactivating alterations in the SWItch/Sucrose NonFermentable (SWI/SNF) Chromatin Remodeling Complex subunits have been described in multiple tumor types. Recent studies focused on SMARC subunits of this complex to understand their relationship with tumor characteristics and therapeutic opportunities. To date, pancreatic cancer with these alterations has not been well studied, although isolated cases of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39094734
DOI: 10.1016/j.modpat.2024.100585
PMCID: PMC11585460

Genes

SMARCB1
SMARCA2
KRAS
SMARCA4
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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SWI/SNF Complex-Deficient Undifferentiated Carcinoma of the Pancreas: Clinicopathologic and Genomic Analysis.PMID 39094734Read ↗

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