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SWI / SNF ‐deficiency defines highly aggressive undifferentiated endometrial carcinoma

30 Oct 2020

Abstract excerpt

Dedifferentiated/undifferentiated endometrial carcinoma (DDEC/UEC) is an endometrial cancer characterized by the presence of histologically undifferentiated carcinoma. Genomic inactivation of core switch/sucrose nonfermentable (SWI/SNF) complex proteins was recently identified in approximately two-thirds of DDEC/UEC. The aim of this study was to delineate the clinical behavior of SWI/SNF-deficient DDEC/UEC in...

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PMID: 33125840
DOI: 10.1002/cjp2.188

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