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Article

KIR2DL1 gene is a surrogate marker of protection against infection-related hospitalization among HIV-1 unexposed versus exposed uninfected infants in Cameroon.

BMC immunology - 1 Aug 2024

Simeni Luc-Aimé Kagoué, Ekali Gabriel Loni, Yengo Clauvis Kunkeng, Wouambo Rodrigue Kamga, Fischer Janett, Bessong Oumarou M'rikam A, Fokam Joseph, Yindom Louis-Marie, Nguedia Jules Clément Assob

Abstract excerpt

BACKGROUND: HIV-exposed uninfected infants (HEU) appear more vulnerable to infections compared to their HIV-unexposed uninfected (HUU) peers, generally attributed to poor passive immunity acquired from the mother. This may be due to some genetic factors that could alter the immune system. We thus sought to determine the distribution of Killer Cell Immunoglobulin-Like Receptors (KIRs) genes in HEU versus HUU and...

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Identifiers

PMID: 39090586
DOI: 10.1186/s12865-024-00645-9
PMCID: PMC11293080

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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