Article
Polymorphisms in IL-1 gene cluster and its association with the risk of perinatal HIV transmission, in an Indian cohort.
Immunology letters - 1 Jun 2013
Ahir Swati, Chaudhari Deepali, Chavan Vijay, Samant-Mavani Padmaja, Nanavati Ruchi, Mehta Preeti, Mania-Pramanik Jayanti
Abstract excerpt
Host genetic diversity plays a very important role in protecting infants exposed to HIV-1 through their mothers. IL-1 family genes are key mediators of inflammatory responses and no studies are available on its association with perinatal HIV transmission. We aimed to evaluate if single nucleotide polymorphisms in IL-1 family genes are associated with perinatal HIV transmission. Infants of HIV positive women were...
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