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Article

Lower mitochondrial DNA and altered mitochondrial fuel metabolism in HIV-exposed uninfected infants in Cameroon

18 Sept 2017

Abstract excerpt

OBJECTIVE: Evaluate blood mitochondrial DNA (mtDNA) content in HIV/antiretroviral-exposed uninfected (HEU) vs. HIV-unexposed uninfected (HUU) infants and investigate differences in mitochondrial-related metabolites by exposure group. DESIGN: We enrolled a prospective cohort of HIV-infected and HIV-uninfected pregnant woman/infant pairs in Cameroon. METHODS: Dried blood spot mtDNA : nuclear DNA ratio was measured...

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PMID: 28926411
DOI: 10.1097/qad.0000000000001647

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