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Article

Trajectories of egg sensitization in childhood: Two birth cohorts in Asia and Europe.

Allergy - 1 Jan 2025

Nakamura Toshinori, Nakano Taiji, Simpson Angela, Kono Michihiro, Curtin John A, Kobayashi Tomoko, Murray Clare S, Akiyama Masashi, Imanishi Masahiro, Mikuriya Masayuki, Custovic Adnan, Shimojo Naoki

Abstract excerpt

BACKGROUND: Hen's egg exposure through impaired skin barrier is considered a major mechanism of sensitization to eggs. However, the impact of filaggrin (FLG) gene loss-of-function mutations on the natural history of egg sensitization lacks consensus among studies. OBJECTIVE: To evaluate the association between the natural course of egg sensitization and FLG mutations. METHODS: We used Japanese and the UK birth...

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Identifiers

PMID: 39087444
DOI: 10.1111/all.16264

Genes

FLG

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