Article
Genetics of coronary artery disease: genome-wide association studies and beyond.
Atherosclerosis - 1 Nov 2012
Prins Bram P, Lagou Vasiliki, Asselbergs Folkert W, Snieder Harold, Fu Jingyuan
Abstract excerpt
Genome-wide association (GWA) studies on coronary artery disease (CAD) have been very successful, identifying a total of 32 susceptibility loci so far. Although these loci have provided valuable insights into the etiology of CAD, their cumulative effect explains surprisingly little of the total CAD heritability. In this review, we first highlight and describe the type of genetic variants potentially underlying...
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