A decade of genome-wide association studies for coronary artery disease: the challenges ahead.

doi:10.1093/cvr/cvy084

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Article

A decade of genome-wide association studies for coronary artery disease: the challenges ahead.

Cardiovascular research - 15 Jul 2018

Erdmann Jeanette, Kessler Thorsten, Munoz Venegas Loreto, Schunkert Heribert

Abstract excerpt

In this review, we summarize current knowledge on the genetics of coronary artery disease, based on 10 years of genome-wide association studies. The discoveries began with individual studies using 200K single nucleotide polymorphism arrays and progressed to large-scale collaborative efforts, involving more than a 100 000 people and up to 40 Mio genetic variants. We discuss the challenges ahead, including those...

Topics

Coronary Artery Disease
Diffusion of Innovation
Forecasting
Genetic Markers
Genetic Predisposition to Disease
Genetic Variation
Genome-Wide Association Study
Heredity
History, 21st Century
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pedigree

Phenotype

Precision Medicine

Predictive Value of Tests

Prognosis

Risk Factors

Source

Open in PubMed

Identifiers

PMID: 29617720
DOI: 10.1093/cvr/cvy084

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