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Article

Genetic Polymorphisms in Glutathione S-Transferase (GST) Gene and Their Correlation with Toxicity of Chemotherapy in Breast Cancer Patients.

Asian Pacific journal of cancer prevention : APJCP - 1 Jul 2024

Gudur Rashmi A, Bhosale Suresh J, Gudur Anand K, Datkhile Kailas D

Abstract excerpt

BACKGROUND: Glutathione S-Transferase (GST) is a family of phase II metabolizing enzymes contribute to detoxification and elimination of variety of endogenous as well as exogenous xenobiotics including chemotherapeutic agents. The comprehensive knowledge on the impact of genetic polymorphisms in GST) enzyme coding gene will help to understand the clinical outcomes in breast cancer patients treated with either...

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Identifiers

PMID: 39068558
DOI: 10.31557/APJCP.2024.25.7.2271
PMCID: PMC11480591

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