Article
Glutathione S-transferase polymorphisms influence chemotherapy response and treatment outcome in breast cancer.
Genetics and molecular research : GMR - 22 Sept 2015
Wang J, Wang T, Yin G-Y, Yang L, Wang Z-G, Bu X-B
Abstract excerpt
The aim of this study was to evaluate the role of GSTM1 null/present, GSTT1 null/present, and GSTP1 IIe105Val polymorphisms in the clinical response to chemotherapy and treatment outcome of patients with breast cancer. A total of 262 subjects were randomly selected from among patients with a histologically confirmed breast cancer. The genotypes of GSTM1, GSTT1, and GSTP1 IIe105Val polymorphisms were determined by...
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