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Article

GWAS-based polygenic risk scoring for predicting cerebral artery dissection in the Chinese population.

BMC neurology - 25 Jul 2024

Zhang Shufan, Zhu Dongliang, Wu Zhengyu, Yang Shilin, Liu Yuanzeng, Kang Xiaocui, Chen Xingdong, Zhu Zhu, Dong Qiang, Suo Chen, Han Xiang

Abstract excerpt

OBJECTIVE: Cerebral artery dissection (CeAD) is a rare but serious disease. Genetic risk assessment for CeAD is lacking in Chinese population. We performed genome-wide association study (GWAS) and computed polygenic risk score (PRS) to explore genetic susceptibility factors and prediction model of CeAD based on patients in Huashan Hospital. METHODS: A total of 210 CeAD patients and 280 controls were enrolled from...

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Identifiers

PMID: 39054468
DOI: 10.1186/s12883-024-03759-0
PMCID: PMC11271197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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