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Article

Genetic diagnosis of acute aortic dissection in South China Han population using next-generation sequencing.

International journal of legal medicine - 1 Sept 2018

Zheng Jinxiang, Guo Jian, Huang Lei, Wu Qiuping, Yin Kun, Wang Lin, Zhang Tongda, Quan Li, Zhao Qianhao, Cheng Jianding

Abstract excerpt

Acute aortic dissection (AAD) is a clinically "silent," but emergent and life-threatening cardiovascular disease, and hereditary factors play an important etiologic role in the development of AAD. The purposes of this study are to definitize the diagnostic yield of 59 AAD patients, investigate the molecular pathological spectrum of AAD by NGS, and explore the future preclinical prospects of genetic diagnosis on...

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Share to Aortic Aneurysm, Thoracic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30056620
DOI: 10.1007/s00414-018-1890-9

Genes

ACTA2
FBN1
ABCC6
CNTN3
MYLK
NOS3
PON1
TGFBR1
TGFBR2
TIMP4
XYLT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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