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Article

Integrative genomic analysis reveals cancer-associated mutations in patients with ophthalmic tumors.

The Journal of international medical research - 1 Jul 2024

Zhu Fengjiao, Wang Pengpeng, Zhang Zhiyuan, Yao Chunlei, Wang Yijie, Ye Juan, Wu Jian

Abstract excerpt

OBJECTIVE: Apart from the role of the retinoblastoma gene, the genomic events associated with poor outcomes in patients with ophthalmic tumors are poorly understood. METHODS: We retrospectively analyzed 48 patients with six types of ophthalmic tumors. We searched for high-frequency mutated genes and susceptibility genes in these patients using combined exome and transcriptome analysis. RESULTS: We identified four...

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Identifiers

PMID: 39053449
DOI: 10.1177/03000605241258171
PMCID: PMC11283671

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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