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Article

Ocular surface squamous neoplasia: Update on genetics, epigenetics and opportunities for targeted therapy.

The ocular surface - 1 Jan 2025

Kounatidou Nefeli Eleni, Vitkos Evangelos, Palioura Sotiria

Abstract excerpt

PURPOSE: The purpose of this review is to explore the molecular foundations of ocular surface squamous neoplasia (OSSN), focusing on the genetic and epigenetic aspects. While current management strategies include surgical excision and medical therapies, the understanding of OSSN's molecular basis remains limited, hindering the development of targeted treatments. METHODS: A comprehensive MEDLINE search was...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39608452
DOI: 10.1016/j.jtos.2024.11.006

Genes

CDKN2A
EGFR
HGF
TERT
TP53

Provenance

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