Article

Diagnostic Value of Genetic Mutation Analysis and Mutation Profiling of cfDNA in Intraocular Fluid for Vitreoretinal Lymphoma

2021-10-19

Abstract excerpt

<h4>Objective</h4> Vitreoretinal lymphoma (VRL) is a rare but aggressive masquerade syndrome, with challenging diagnosis. Since the tumor-related genetic mutation analysis based on cell-free DNA (cfDNA) are underutilized in ocular oncology, we aimed to test the VRL diagnostic value of cfDNA genetic mutation analysis using intraocular fluid (IOF) samples and to identify its mutation profile. <h4>Subjects</h4> Sev...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: abbffe03-8273-5bb5-b6c1-d3702fc07338
DOI: 10.1101/2021.10.18.21265102

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Diagnostic Value of Genetic Mutation Analysis and Mutation Profiling of cfDNA in Intraocular Fluid for Vitreoretinal LymphomaDOI 10.1101/2021.10.18.21265102Read

Diagnostic potential of vitreoretinal lymphoma by detection of gene mutations with NGS in 25 Chinese patients.Semantic proximity Read

Emerging diagnostic tests for vitreoretinal lymphoma: a review.Semantic proximity Read

Impact of genetic alterations on central nervous system progression of primary vitreoretinal lymphoma.Semantic proximity Read

A pilot study of the use of dynamic analysis of cell-free DNA from aqueous humor and vitreous fluid for the diagnosis and treatment monitoring of vitreoretinal lymphomasSemantic proximity Read

Next-Generation Sequencing of Vitreoretinal Lymphoma by Vitreous Liquid Biopsy: Diagnostic Potential and Genotype/Phenotype Correlation.Semantic proximity Read

Deep sequencing as a diagnostic tool in patients with suspected primary vitreoretinal lymphomaSemantic proximity Read

Challenges in the diagnosis and management of vitreoretinal lymphoma - Clinical and basic approaches.Semantic proximity Read

Mutation Profiling of Malignant Lymphoma by Next-Generation Sequencing of Circulating Cell-Free DNASemantic proximity Read

Next generation sequencing of vitreoretinal lymphomas from small-volume intraocular liquid biopsies: new routes to targeted therapies.Semantic proximity Read

Comparison of the Diagnostic Significance of CSF Metagenomic Next-generation Sequencing Copy Number Variation Analysis and Cytology in Leptomeningeal MalignancySemantic proximity Read

Detection of genes mutations in cerebrospinal fluid circulating tumor DNA from neoplastic meningitis patients using next generation sequencingSemantic proximity Read

Heterogeneity and molecular landscape of melanoma: implications for targeted therapy.Semantic proximity Read