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Article

Gene association analysis to determine the causal relationship between immune cells and juvenile idiopathic arthritis.

Pediatric rheumatology online journal - 8 Mar 2024

Chen Longhao, Zhou Xingchen, Yang Chao, Wu Hong Jiao, Tian Yu, Hong Shuangwei, Hu Huijie, Wang Kaizheng, Wu Shuang, Wei Zicheng, Li Tao, Huang Yuanshen, Hua Zihan, Xia Qiong, Chen Xiao Jie, Lv Zhizhen, Lv Lijiang

Abstract excerpt

BACKGROUND: Juvenile idiopathic arthritis (JIA) is a type of chronic childhood arthritis with complex pathogenesis. Immunological studies have shown that JIA is an acquired self-inflammatory disease, involving a variety of immune cells, and it is also affected by genetic and environmental susceptibility. However, the precise causative relationship between the phenotype of immune cells and JIA remains unclear to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38459548
DOI: 10.1186/s12969-024-00970-8
PMCID: PMC10921670

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