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Article

Ataxin-2: From RNA Control to Human Health and Disease

5 Jun 2017

Abstract excerpt

RNA-binding proteins play fundamental roles in the regulation of molecular processes critical to cellular and organismal homeostasis. Recent studies have identified the RNA-binding protein Ataxin-2 as a genetic determinant or risk factor for various diseases including spinocerebellar ataxia type II (SCA2) and amyotrophic lateral sclerosis (ALS), amongst others. Here, we first discuss the increasingly wide-ranging...

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PMID: 28587229
DOI: 10.3390/genes8060157

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