Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unraveling the interaction between stress and genetic risk in psychiatric disorders: Challenges, mechanisms, and new advances.

Neuron - 1 Jul 2026

Penner-Goeke Signe, Binder Elisabeth B

Abstract excerpt

Exposure to stress is a fundamental aspect of human life but is also linked to increased risk for various psychiatric and medical disorders. However, not all individuals exposed to stress experience the same outcomes, underscoring the complex interactions between stress exposure and genetic predisposition. Numerous studies employing diverse methodologies emphasize the significance of gene-stress interactions in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene-Environment Interaction
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mental Disorders

Share to Stress, Psychological

Source

Identifiers

PMID: 41895268
DOI: 10.1016/j.neuron.2026.02.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unraveling the interaction between stress and genetic risk in psychiatric disorders: Challenges, mechanisms, and new advances.PMID 41895268Read ↗

Gene-environment interaction and psychiatric disorders: Review and future directions.Semantic proximity Read ↗

Gene × Environment Determinants of Stress- and Anxiety-Related Disorders.Semantic proximity Read ↗

Genetics of stress response and stress-related disordersSemantic proximity Read ↗

Genetic opportunities for psychiatric epidemiology: on life stress and depression.Semantic proximity Read ↗

Epigenetics of Stress-Related Psychiatric Disorders and Gene × Environment InteractionsSemantic proximity Read ↗

Common genetic variation impacts stress response in the brainSemantic proximity Read ↗

Interactions of early-life stress with the genome and epigenome: from prenatal stress to psychiatric disordersSemantic proximity Read ↗

Prenatal stress and genetic risk: How prenatal stress interacts with genetics to alter risk for psychiatric illness.Semantic proximity Read ↗

Stress-related exposures amplify the effects of genetic susceptibility on depression and anxiety.Semantic proximity Read ↗

Genetic Predisposition and Genetic Resilience Factors in Stress-Related Disorders During the Developmental Age: A Narrative Review.Semantic proximity Read ↗

Genome-wide stress sensitivity moderates the stress-depression relationship in a nationally representative sample of adults.Semantic proximity Read ↗

Gene-environment interplay and psychopathology: multiple varieties but real effects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.