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Article

Common genetic variation impacts stress response in the brain

2023-12-28

Abstract excerpt

<h4>ABSTRACT</h4> To explain why individuals exposed to identical stressors experience divergent clinical outcomes, we determine how molecular encoding of stress modifies genetic risk for brain disorders. Analysis of post-mortem brain (n=304) revealed 8557 stress-interactive expression quantitative trait loci (eQTLs) that dysregulate expression of 915 eGenes in response to stress, and lie in stress-related transc...

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Identifiers and source

Literature Corpus work
1db8ab4e-cdd4-5a59-8e45-3489834fd88a
DOI
10.1101/2023.12.27.573459
Open publication

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Common genetic variation impacts stress response in the brainDOI 10.1101/2023.12.27.573459
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