Article
Transient early wheeze and lung function in early childhood associated with chronic obstructive pulmonary disease genes.
The Journal of allergy and clinical immunology - 1 Jan 2014
Kerkhof Marjan, Boezen H Marike, Granell Raquel, Wijga Alet H, Brunekreef Bert, Smit Henriëtte A, de Jongste Johan C, Thijs Carel, Mommers Monique, Penders John, Henderson John, Koppelman Gerard H, Postma Dirkje S
Abstract excerpt
BACKGROUND: It has been hypothesized that a disturbed early lung development underlies the susceptibility to chronic obstructive pulmonary disease (COPD). Little is known about whether subjects genetically predisposed to COPD show their first symptoms or reduced lung function in childhood. OBJECTIVE: We investigated whether replicated genes for COPD associate with transient early wheeze (TEW) and lung function...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.