Article
Mitochondrial DNA Heteroplasmy Associations With Neurosensory and Mobility Function in Elderly Adults
31 Aug 2015
Abstract excerpt
BACKGROUND: Mitochondrial DNA (mtDNA) heteroplasmy is a mixture of normal and mutated mtDNA molecules in a cell. High levels of heteroplasmy at specific mtDNA sites lead to inherited mitochondrial diseases with neurological, sensory, and movement impairments. Here we test the hypothesis that heteroplasmy levels in elderly adults are associated with impaired function resembling mild forms of mitochondrial disease....
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