Regulation of MicroRNA-4697-3p by Parkinson's disease-associated SNP rs329648 and its impact on SNCA112 mRNA.

doi:10.1007/s11033-024-09725-w

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Regulation of MicroRNA-4697-3p by Parkinson's disease-associated SNP rs329648 and its impact on SNCA112 mRNA.

Molecular biology reports - 13 Jul 2024

Yoo Myungsik, Bunkowski Klaudia, Lie Andrew, Junn Eunsung

Abstract excerpt

BACKGROUND: Parkinson's disease (PD) is a common neurodegenerative disorder characterized by a multifaceted genetic foundation. Genome-Wide Association Studies (GWAS) have played a crucial role in pinpointing genetic variants linked to PD susceptibility. Current study aims to delve into the mechanistic aspects through which the PD-associated Single Nucleotide Polymorphism (SNP) rs329648, identified in prior GWAS,...

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PMID: 39001947
DOI: 10.1007/s11033-024-09725-w

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