Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hypomethylation of the RUNX2 Gene Is a New Potential Biomarker of Primary Osteoporosis in Men and Women

3 Jul 2024

Abstract excerpt

The search for the molecular markers of osteoporosis (OP), based on the analysis of differential deoxyribonucleic acid (DNA) methylation in bone cells and peripheral blood cells, is promising for developments in the field of the early diagnosis and targeted therapy of the disease. The Runt-related transcription factor 2 (RUNX2) gene is one of the key genes of bone metabolism, which is of interest in the search...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone and Joint Diseases
Share to Bone health and treatments
Share to Bone Metabolism and Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39000419
DOI: 10.3390/ijms25137312

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hypomethylation of the RUNX2 Gene Is a New Potential Biomarker of Primary Osteoporosis in Men and WomenPMID 39000419Read ↗

Influence of DNA methylation on the expression of OPG/RANKL in primary osteoporosisSemantic proximity Read ↗

Role of the Vitamin D Receptor (VDR) in the Pathogenesis of Osteoporosis: A Genetic, Epigenetic and Molecular Pilot StudySemantic proximity Read ↗

The lower methylation of RANK is associated with osteoporosis in male aged general population of Xinjiang: A Case-Control StudySemantic proximity Read ↗

Identification of an Epigenetic Signature of Osteoporosis in Blood DNA of Postmenopausal WomenSemantic proximity Read ↗

Exploring DNA methylation profiles in the pathogenesis of human osteoporosis via whole-genome bisulfite sequencingSemantic proximity Read ↗

Role of DNA methylation in the regulation of the RANKL-OPG system in human boneSemantic proximity Read ↗

RUNX2: A Master Bone Growth Regulator That May Be Involved in the DNA Damage ResponseSemantic proximity Read ↗

Exploring DNA methylation profiles in the pathogenesis of human osteoporosis via whole-genome bisulfite sequencingSemantic proximity Read ↗

Association of a RUNX2 promoter polymorphism with bone mineral density in postmenopausal Korean women.Semantic proximity Read ↗

Hypomethylation of Alu elements in post-menopausal women with osteoporosis.Semantic proximity Read ↗

Promoter 2 -1025 T/C polymorphism in the RUNX2 gene is associated with femoral neck bmd in Spanish postmenopausal women.Semantic proximity Read ↗

Causal impact of DNA methylation on refracture in elderly individuals with osteoporosis – a prospective cohort studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.