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Article

Role of DNA methylation in the regulation of the RANKL-OPG system in human bone

1 Jan 2012

Abstract excerpt

Osteoblasts are specialized cells that form new bone and also indirectly influence bone resorption by producing factors that modulate osteoclast differentiation. Although the methylation of CpG islands plays an important role in the regulation of gene expression, there is still scanty information about its role in human bone. The aim of this study was to investigate the influence of CpG methylation on the...

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PMID: 22207352
DOI: 10.4161/epi.7.1.18753

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