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Role of the Vitamin D Receptor (VDR) in the Pathogenesis of Osteoporosis: A Genetic, Epigenetic and Molecular Pilot Study

21 Feb 2023

Abstract excerpt

The vitamin D receptor (VDR) regulates bone development and calcium homeostasis, suggesting a central role in musculoskeletal diseases such as osteoporosis (OP). Several studies have examined the contribution of VDR polymorphisms and epigenetic signatures in bone metabolism and OP risk, with sometimes inconclusive results. Our study aimed to explore the association between genetic variability, expression and the...

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Bone health and osteoporosis research
Folate and B Vitamins Research
Vitamin D Research Studies

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36980815
DOI: 10.3390/genes14030542

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Role of the Vitamin D Receptor (VDR) in the Pathogenesis of Osteoporosis: A Genetic, Epigenetic and Molecular Pilot StudyPMID 36980815Read ↗

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