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Article

Hypomethylation of Alu elements in post-menopausal women with osteoporosis.

PloS one - 1 Jan 2013

Jintaridth Pornrutsami, Tungtrongchitr Rungsunn, Preutthipan Sangchai, Mutirangura Apiwat

Abstract excerpt

A decrease in genomic methylation commonly occurs in aging cells; however, whether this epigenetic modification leads to age-related phenotypes has not been evaluated. Alu elements are the major interspersed repetitive DNA elements in humans that lose DNA methylation in aging individuals. Alu dem...

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Identifiers

PMID: 23990903
DOI: 10.1371/journal.pone.0070386
PMCID: PMC3749148

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23990903-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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