Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RUNX2: A Master Bone Growth Regulator That May Be Involved in the DNA Damage Response

2 Jan 2015

Abstract excerpt

RUNX2 is a member of the RUNX family of transcription factors, also containing the RUNX1 and RUNX3 proteins. These factors control the expression of genes essential for proper development in many cell lineages. RUNX2 plays a crucial role in the proliferation and differentiation of osteoblasts, required for bone formation. The cellular level of RUNX2 oscillates in a cell phase-specific manner, reaching a maximum...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone health and treatments
Share to Bone Metabolism and Diseases
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25555110
DOI: 10.1089/dna.2014.2688

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RUNX2: A Master Bone Growth Regulator That May Be Involved in the DNA Damage ResponsePMID 25555110Read ↗

The RUNX Family of Proteins, DNA Repair, and CancerSemantic proximity Read ↗

Role and regulation of RUNX2 in osteogenesisSemantic proximity Read ↗

RUNX Family as a Promising Biomarker and a Therapeutic Target in Bone Cancers: A Review on Its Molecular Mechanism(s) behind TumorigenesisSemantic proximity Read ↗

The RUNX Family, a Novel Multifaceted Guardian of the GenomeSemantic proximity Read ↗

Runx2: A master organizer of gene transcription in developing and maturing osteoblastsSemantic proximity Read ↗

Runx2 in normal tissues and cancer cells: A developing storySemantic proximity Read ↗

RUNX family: Oncogenes or tumor suppressors (Review)Semantic proximity Read ↗

Runt-related transcription factor 2 (RUNX2) inhibits p53-dependent apoptosis through the collaboration with HDAC6 in response to DNA damageSemantic proximity Read ↗

Runx2, a multifunctional transcription factor in skeletal development.Semantic proximity Read ↗

Genetic Studies of Bone Diseases: Evidence for Involvement of DNA Damage Response Proteins in Bone RemodelingSemantic proximity Read ↗

[Cbfa1/Runx2, an essential transcription factor for the regulation of osteoblast differentiation].Semantic proximity Read ↗

Transcriptional Regulatory Cascades in Runx2-Dependent Bone DevelopmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.