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Article

Prioritizing drug targets in systemic lupus erythematosus from a genetic perspective: a druggable genome-wide Mendelian randomization study.

Clinical rheumatology - 1 Sept 2024

Gao Yuan, Zhou Youtao, Lin Zikai, Chen Fengzhen, Wu Haiyang, Peng Chusheng, Xie Yingying

Abstract excerpt

OBJECTIVES: Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease with an unsatisfactory state of treatment. We aim to explore novel targets for SLE from a genetic standpoint. METHODS: Cis-expression quantitative trait loci (eQTLs) for whole blood from 31,684 samples provided by the eQTLGen Consortium as well as two large SLE cohorts were utilized for screening and validating genes causally...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lupus Erythematosus, Systemic

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Source

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Identifiers

PMID: 38997544
DOI: 10.1007/s10067-024-07059-3
PMCID: PMC11330408

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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