Article
Macrophage-derived exosomes promote telomere fragility and senescence in tubular epithelial cells by delivering miR-155
10 Jul 2024
Abstract excerpt
Abstract Background Chronic kidney disease (CKD) is highly prevalent worldwide, and its global burden is substantial and growing. CKD displays a number of features of accelerated senescence. Tubular cell senescence is a common biological process that contributes to CKD progression. Tubulointerstitial inflammation is a driver of tubular cell senescence and a common characteristic of CKD. However, the mechanism by...
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