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Article

Molecular aspects of renal senescence

1 Jul 2015

Abstract excerpt

PURPOSE OF REVIEW: The aging kidney undergoes profound changes that lead to a reduction in stress resistance and impaired repair capacity. In order to improve the outcome of acute and chronic kidney damage, it is instrumental to understand the mechanisms that cause these changes. Cellular senescence has emerged as an important cellular process that contributes to age-associated kidney changes and chronic kidney...

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PMID: 26126196
DOI: 10.1097/mot.0000000000000214

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