Article
Are weight loss and metabolic outcomes of bariatric surgery influenced by candidate glucocorticoid receptor gene polymorphisms? A prospective study.
Adipocyte - 1 Dec 2024
Iqbal Zohaib, Vasan Senthil Kandaswamy, Fachim Helene, Warner-Levy John, Donn Rachelle P, Ammori Basil J, Heald Adrian H, Soran Handrean, Syed Akheel A
Abstract excerpt
BACKGROUND: Bariatric surgery is the most effective treatment for severe obesity. There can be variation in the degree of weight reduction following bariatric surgery. It is unknown whether single nucleotide polymorphisms (SNPs) in the glucocorticoid receptor locus (GRL) affect postoperative weight loss and metabolic outcomes. MATERIALS/METHODS: We studied the association between selected candidate SNPs and...
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