Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recombinant Human IL-32θ Induces Polarization Into M1-like Macrophage in Human Monocytic Cells

1 Jan 2024

Abstract excerpt

The tumor microenvironment (TME) is formed by several immune cells.Notably, tumorassociated macrophages (TAMs) are existed in the TME that induce angiogenesis, metastasis, and proliferation of cancer cells.Recently, a point-mutated variant of IL-32θ was discovered in breast cancer tissues, which suppressed migration and proliferation through intracellular pathways.Although the relationship between cancer and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Immune cells in cancer
Share to Phagocytosis and Immune Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38974209
DOI: 10.4110/in.2024.24.e27

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Recombinant Human IL-32θ Induces Polarization Into M1-like Macrophage in Human Monocytic CellsPMID 38974209Read ↗

Chemokine-Induced Macrophage Polarization in Inflammatory ConditionsSemantic proximity Read ↗

Activating a collaborative innate-adaptive immune response to control breast and ovarian cancer metastasisSemantic proximity Read ↗

Macrophage Differentiation and Polarization into an M2-Like Phenotype using a Human Monocyte-Like THP-1 Leukemia Cell Line.Semantic proximity Read ↗

Exosome-mediated miR-33 transfer induces M1 polarization in mouse macrophages and exerts antitumor effect in 4T1 breast cancer cell line.Semantic proximity Read ↗

M2 macrophages contribute to cell proliferation and migration of breast cancerSemantic proximity Read ↗

Influence of tumor cell culture supernatants on macrophage functional polarization: in vitro models of macrophage-tumor environment interaction.Semantic proximity Read ↗

TGF-β type I receptor inhibitor suppresses polarization of tumor-associated macrophages to the M2 phenotype and exerts antitumor effects on colorectal cancerSemantic proximity Read ↗

Polysaccharides of Brassica rapa L. attenuate tumor growth via shifting macrophages to M1-like phenotype.Semantic proximity Read ↗

TRAIL promotes the polarization of human macrophages toward a proinflammatory M1 phenotype and is associated with increased survival in cancer patients with high tumor macrophage contentSemantic proximity Read ↗

Triple-negative breast cancer influences a mixed M1/M2 macrophage phenotype associated with tumor aggressiveness.Semantic proximity Read ↗

Gremlin 1 is required for macrophage M2 polarizationSemantic proximity Read ↗

TRAIL promotes the polarization of human macrophages toward a proinflammatory M1 phenotype and is associated with increased survival in cancer patients with high tumor macrophage content.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.