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Article

Causal relationship and shared genes between air pollutants and amyotrophic lateral sclerosis: A large-scale genetic analysis.

CNS neuroscience & therapeutics - 1 Jul 2024

Li Zhihao, Wen Jie, Wu Wantao, Dai Ziyu, Liang Xisong, Zhang Nan, Cheng Quan, Zhang Hao

Abstract excerpt

OBJECTIVE: Air pollutants have been reported to have a potential relationship with amyotrophic lateral sclerosis (ALS). The causality and underlying mechanism remained unknown despite several existing observational studies. We aimed to investigate the potential causality between air pollutants (PM2.5, NOX, and NO2) and the risk of ALS and elucidate the underlying mechanisms associated with this relationship....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38970158
DOI: 10.1111/cns.14812
PMCID: PMC11226412

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