Article
Identification of risk factors associated with onset and progression of amyotrophic lateral sclerosis using systematic review and meta-analysis.
Neurotoxicology - 1 Jul 2017
Wang Ming-Dong, Little Julian, Gomes James, Cashman Neil R, Krewski Daniel
Abstract excerpt
Although amyotrophic lateral sclerosis (ALS) was identified as a neurological condition 150 years ago, risk factors related to the onset and progression of ALS remain largely unknown. Monogenic mutations in over 30 genes are associated with about 10% of ALS cases. The age at onset of ALS and disease types has been found to influence ALS progression. The present study was designed to identify additional putative...
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