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Article

WT1 gene mutations impact post-transplant relapse in myelodysplastic syndrome with excess blasts 2 patients.

Annals of hematology - 1 Aug 2024

Guo Wenwen, Zhang Haixiao, Wang Mingyang, Zheng Yawei, Cao Yigeng, Zhang Xiaoyu, Zhai Weihua, Zhang Rongli, Yang Donglin, Wei Jialin, He Yi, Ma Qiaoling, Xia Yonghui, Pang Aiming, Feng Sizhou, Han Mingzhe, Jiang Erlie

Abstract excerpt

Wilms tumor 1 (WT1) gene mutations are infrequent in myelodysplastic syndrome (MDS), but MDS with WT1 mutations (WT1mut) is considered high risk for acute myeloid leukemia (AML) transformation. The influence of WT1 mutations in patients with MDS after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is unclear. We performed a retrospective analysis of 136 MDS with excess blasts 2 (MDS-EB2) patients...

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Identifiers

PMID: 38969929
DOI: 10.1007/s00277-024-05870-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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