Article
Acute Myeloid Leukemia Patients With Myelodysplasia-Related Gene Mutations Benefit From Post-Transplant Hypomethylating Agent Maintenance.
Transplantation and cellular therapy - 1 May 2026
Huang Jiayu, Xia Yi, Xiang Mengqi, Zhang Ran, Yang Yang, Chen Hongru, Dong Changwei, Li Su, Zhu Jun, Jin Chengwei, Wang Luxiang, Jiang Chuanhe, Huo Wenxuan, Pan Zengkai, Ma Yilei, Lu Haiyang, Tian Ze, Zhang Zilu, Zhang Jianping, Chen Chen, Cao Weijie, Shi Wei, Zhao Yanmin, Chen Jia, Cao Yang, Mo Xiaodong, Hu Xiaoxia
Abstract excerpt
Relapse remains the major cause of mortality in adverse-risk acute myeloid leukemia (AML) patients receiving allogeneic hematopoietic stem cell transplantation (allo-HSCT). Hypomethylating agent (HMA) maintenance is a strategy to prevent post-transplant relapse, but its value among different genetically defined subgroups is still controversial. The study was designed to evaluate the efficacy of HMA maintenance in...
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