Article
Mutation Profile via Next-Generation Sequencing in Patients with Colorectal Adenocarcinoma and Its Clinicopathological Correlation.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology - 1 Nov 2023
Osman Sibel, Kahraman Çetin Nesibe, Erdoğdu İbrahim Halil, Meteoğlu İbrahim
Abstract excerpt
BACKGROUND/AIMS: Recent studies that reveal the molecular profiles of colorectal carcinomas have demonstrated tumor heterogeneity. Characterization of colorectal carcinoma-specific genomic alterations is essential for developing more successful and targeted treat- ment protocols. Moreover, it is vital in elucidating the pathogenesis and mechanisms of resistance against treatment and predicting prognosis....
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