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Article

Genetic evidence supports a causal relationship between air pollution and brain imaging-derived phenotypes.

Ecotoxicology and environmental safety - 1 Aug 2024

Wang Qitong, Li Shuzhu, Cai Benchi, Zhong Lifan, Liu Fang, Wang Xinyu, Chen Tao

Abstract excerpt

BACKGROUND: Observational studies have reported associations between air pollutants and brain imaging-derived phenotypes (IDPs); however, whether this relationship is causal remains uncertain. METHODS: We conducted bidirectional two-sample Mendelian randomization (MR) analyses to explore the causal relationships between 5 types of air pollutants (N=423,796 to 456,380 individuals) and 587 reliable IDPs (N=33,224...

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Identifiers

PMID: 38954909
DOI: 10.1016/j.ecoenv.2024.116664

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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