Article
The association between air pollutant exposure and cerebral small vessel disease imaging markers with modifying effects of PRS-defined genetic susceptibility.
Ecotoxicology and environmental safety - 1 Aug 2024
Sun Xiaowei, Ma Shiyang, Guo Yunlu, Chen Caiyang, Pan Lijun, Cui Yidan, Chen Zengai, Dijkhuizen Rick M, Zhou Yan, Boltze Johannes, Yu Zhangsheng, Li Peiying
Abstract excerpt
Studies have highlighted a possible link between air pollution and cerebral small vessel disease (CSVD) imaging markers. However, the exact association and effects of polygenic risk score (PRS) defined genetic susceptibility remains unclear. This cross-sectional study used data from the UK Biobank. Participants aged 40-69 years were recruited between the year 2006 and 2010. The annual average concentrations of...
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